Journal Covers

loc2014P
iecr2018P
nanolet2020P

Journal Publications

  1. Modha, S.*, Shen, Y.*, Chamouni, H., Mulchandani, A., and Tsutsui, H. (2021) Laser-etched grooves for rapid fluid delivery for a paper-based chemiresistive biosensor. Biosensors and Bioelectronics. 180:113090. doi.org/10.1016/j.bios.2021.113090.
  2. Roper, J., Garcia, J., and Tsutsui, H. (2021) Emerging technologies for monitoring plant health in vivo. ACS Omega. doi.org/10.1021/acsomega.0c05850.
  3. Modha, S., Castro, C., and Tsutsui, H. (2021) Recent developments in flow modeling and fluid control for paper-based microfluidic biosensors. Biosensors and Bioelectronics. 178:113026. doi.org/10.1016/j.bios.2021.113026.
  4. Shen, Y., Modha, S., Tsutsui, H., and Mulchandani, A. (2021) An origami electrical biosensor for multiplexed analyte detection in body fluids. Biosensors and Bioelectronics. 171:112721. doi:10.1016/j.bios.2020.112721.
  5. Kalish, B., Tan, M.K., and Tsutsui, H. (2020) Modifying wicking speeds in paper-based microfluidic devices by laser-etching. Micromachines. 11(8):773. doi:10.3390/mi11080773.
  6. Ghasemian, M., Layton, C., Nampe, D., zur Nieden, N.I., Tsutsui, H., and Princevac, M. (2020) Hydrodynamic characterization within a spinner flask and a rotary wall vessel for stem cell culture. Biochemical Engineering Journal. 157:107533. doi:10.1016/j.bej.2020.107533.
  7. Dixit, H.G., Starr, R., Dundon, M.L., Pairs, P.I., Yang, X., Zhang, Y., Nampe, D., Ballas, C.B., Tsutsui, H., Forman, S.J., Brown, C.E., and Rao, M.P. (2020) Massively-parallelized, deterministic mechanoporation for intracellular delivery. Nano Letters. 20(2):860-867. doi:10.1021/acs.nanolett.9b03175. (Selected as a supplemental cover art)
  8. Tsutsui, H., and Lillehoj, P.B. (2020) Flexible analytical devices for point-of-care testing. SLAS Technology. 25(1):6-8. doi:10.1177/2472630319896762. (Guest Editors' Column)
  9. Kalish, B., Zhang, J., Edema, H., Luong, J., Roper, J., Beaudette, C., Echodu, R., and Tsutsui, H. (2020) Distance and microsphere aggregation-based DNA detection in a paper-based microfluidic device. SLAS Technology. 25(1):58-66. doi:10.1177/2472630319887680.
  10. Shen, Y., Thien, T.T., Modha, S., Tsutsui, H., and Mulchandani, A. (2019) A paper-based single-walled carbon nanotubes chemiresistive biosensor for low-cost, point-of-care detection. Biosensors and Bioelectronics. 130:367-373. doi:10.1016/j.bios.2018.09.041.
  11. Peck, R.A, Bahena, E., Jahan, R., Aguilar, G., Tsutsui, H., Princevac, M., Wilhelmus, M.M., and Rao, M.P. (2018) Meso-scale particle image velocimetry studies of neurovascular flows in vitro. Journal of Visualized Experiments. 142:e58902. doi:10.3791/58902.
  12. Wen, J.T., Roper, J.M., and Tsutsui, H. (2018) Polydiacetylene supramolecules: Synthesis, characterization, and emerging applications. Industrical and Engineering Chemistry Research. 57(28):9037-9053. doi:10.1021/acs.iecr.8b00848. (Contribution to the 2018 Class of Influential Researchers Special Issue)
  13. Nampe, D., Joshi, R., Keller, K., zur Nieden, N., and Tsutsui, H. (2017) Impact of fluidic agitation on human pluripotent stem cells in stirred suspension culture. Biotechnology and Bioengineering. 114(9):2109-2120. doi:10.1002/bit.26334.
  14. Castro, C., Rosillo, C., and Tsutsui, H. (2017) Characterizing effects of humidity and channel size on imbibition in paper-based microfluidic channels.Microfluidics and Nanofluidics. 21:21. doi:10.1007/s10404-017-1860-4.
  15. Wen, J., Viravathana, P., Ingel, B., Roper, C., and Tsutsui, H. (2017) Polydiacetylene-coated sensor strip for immunochromatic detection of Xylella fastidiosa subsp. fastidiosa.SLAS Technology. 22(4):406-412. doi:10.1177/2472630316689286.
  16. Wen, J., Bohorquez, K., and Tsutsui, H. (2016) Polydiacetylene-coated polyvinylidene fluoride strip aptasensor for colorimetric detection of zinc(II). Sensors and Actuators B: Chemical. 232:313–317. doi:10.1016/j.snb.2016.03.118.
  17. Kalish, B. and Tsutsui, H. (2016) Using adhesive patterning to construct 3D paper microfluidic devices. Journal of Visualized Experiments. 110:e53805. doi:10.3791/53805.
  18. Wen, J., Castro, C., and Tsutsui, H. (2015) In planta microsphere-based lateral flow leaf biosensor in maize. Journal of Laboratory Automation. 20(4):500-505. doi:10.1177/2211068214551826.
  19. Kalish, B., and Tsutsui, H. (2014) Patterned adhesive enables construction of nonplanar three-dimensional paper microfluidic circuits. Lab on a Chip. 14:4354-4361. doi:10.1039/C4LC00730A. (Selected as a back cover)
  20. Nampe, D., and Tsutsui, H. (2013) Engineered micromechanical cues affecting human pluripotent stem cell regulations and fate. Journal of Laboratory Automation. 18(6):482-493. doi:10.1177/2211068213503156
  21. Chiou, E.P.-Y., and Tsutsui, H. (2013) Advancements in biomedical micro/nano tools and technology. Journal of Laboratory Automation. 18(6):425-426. doi:10.1177/2211068213505834. (Guest Editors' Column)
  22. Valamehr, B., Tsutsui, H., Ho, C.M., and Wu, H. (2011) Developing defined culture systems for human pluripotent stem cells. Regenerative Medicine. 6:623-634. doi:10.2217/rme.11.54
  23. Tsutsui, H.*, Valamehr, B.*, Hindoyan, A., Qiao, R., Ding, X., Guo, S., Witte, O.N., Liu, X., Ho, C.M., and Wu, H. (2011) An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells. Nature Communications. 2:167. doi:10.1038/ncomms1165.
  24. Tsutsui, H., Yu, E., Marquina, S., Valamehr, B., Wong, I., Wu, H., and Ho, C.M. (2010) Efficient dielectrophoretic patterning of embryonic stem cells in energy landscapes defined by hydrogel geometries. Annals of Biomedical Engineering. 38:3777-3788. doi:10.1007/s10439-010-0108-1.
  25. Lillehoj, P.B., Tsutsui, H., Valamehr, B., Wu, H., and Ho, C.M. (2010) Continuous sorting of heterogeneous-sized embryoid bodies. Lab on a Chip. 10:1678–1682. doi:10.1039/C000163E.
  26. Tsutsui, H., and Ho, C.M. (2009) Cell separation by non-inertial force fields in microfluidic systems Mechanics Research Communications. 36:92-103. doi:10.1016/j.mechrescom.2008.08.006
  27. Nomura, K.K., Tsutsui, H., Mahoney, D., and Rottman, J.W. (2006) Short-wavelength instability and decay of a vortex pair in a stratified fluid. Journal of Fluid Mechanics. 553:283-322. doi:10.1017/S0022112006008883.

    28. * The authors contributed equally.

Conference Proceedings and Presentations

  1. Nampe, D., Joshi, R., Karam, J., Keller, K., zur Nieden, N.I., and Tsutsui, H., "Use of hydrodynamic force in stirred suspension culture of human pluripotent stem cells to regulate expansion and differentiation," 2018 SLAS 7th Annual Internatioinal Conference & Exhibition. San Diego, CA, Feb. 3-7, 2018.
  2. Dixit, H.G., Starr, R., Zhang, Y., Nampe, D., Ballas, C. B., Tsutsui, H., Brown, C., Forman, S. J., and Rao, M.P., "Intracellular delivery via ultrahigh throughput mechanoporation for cell therapy applications." The 18th Annual UC Systemwide Bioengineering Symposium, Los Angeles, CA, Jun. 28-30, 2017.
  3. Kalish, B., Tan, M.K., and Tsutsui, H., "Faster wicking in laser-etched paper-based microfluidic channels," The 18th Annual UC Systemwide Bioengineering Symposium, Los Angeles, CA, Jun. 28-30, 2017.
  4. Dixit, H.G., Starr, R., Nampe, D., Zhang, Y., Ballas, C. B., Tsutsui, H., Forman, S. J., and Rao, M.P., "Recent progress towards ultrahigh throughput microinjection," The 12th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS). Los Angeles, CA, Apr. 9-12, 2017.
  5. Kalish, B., Luong, J., Roper, J., Beaudette, C., and Tsutsui, H., "Distance-based quantitative DNA detection in a paper-based microfluidic device," The 12th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS). Los Angeles, CA, Apr. 9-12, 2017.
  6. Dixit, H.G., Starr, R., Zhang, Y., Nampe, D., Ballas, C. B., Tsutsui, H., Brown, C., Forman, S. J., Rao, M.P. "Intracellular delivery via ultrahigh throughput mechanoporation for cell therapy applications," 2017 MRS Spring Meeting & Exhibit, Phoenix, AZ, Apr. 17-21, 2017.
  7. Dixit, H.G., Nampe, D., Tsutsui, H., Rao, M.P., "Intracellular delivery of exogenous molecules via ultrahigh throughput mechanoporation," 2016 MRS Spring Meeting. Phoenix, AZ, Mar. 28-Apr. 1, 2016.
  8. Wen, J., Bohorquez, K., Tsutsui , H., "Polydiacetylene-coated polyvinylidene fluoride strip aptasensor for chromatic detection of zinc(II)," 2016 SLAS 5th Annual Internatioinal Conference & Exhibition. San Diego, CA, Jan. 23-27, 2016.
  9. Castro, C., Rosillo, C., Tsutsui , H., "New model to accurately predict fluid wicking in paper microfluidic devices," 2016 SLAS 5th Annual Internatioinal Conference & Exhibition. San Diego, CA, Jan. 23-27, 2016.
  10. Nampe, D., Joshi, R., Karam, J., Gonzalez, M., Tsutsui, H., "Controlling agitation for expansion and differentiation of human pluripotent stem cells in suspension culture," 2016 SLAS 5th Annual Internatioinal Conference & Exhibition. San Diego, CA, Jan. 23-27, 2016.
  11. Kalish, B. and Tsutsui, H., "Origami-inspired nonplanar three-dimensional paper microfluidic circuits," The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Austin, TX, Oct. 26-30, 2014, pp.1598-1600.
  12. Castro, C., Rosillo, C., and Tsutsui, H., "Predicting wicking in wax-bound paper microfluidic channels," BMES 2014 Annual Fall Meeting, San Antonio, TX, Oct. 23-25, 2014.
  13. Nampe, D., Joshi, R., Beaudette, C., Liew, C., and Tsutsui, H., "Influence of agitation rate and aggregate size on human pluripotent stem cells in dynamic suspension," BMES 2014 Annual Fall Meeting, San Antonio, TX, Oct. 23-25, 2014.
  14. Kalish, B., Tsutsui, H., "Nonplanar three-dimensional paper microfluidic circuits constructed with patterned adhesive," BMES 2014 Annual Fall Meeting, San Antonio, TX, Oct. 23-25, 2014.
  15. Nampe, D., Joshi, R., Beaudette, C., Liew, C.G., and Tsutsui, H., “Investigating the impact of fluidic agitation on human pluripotent stem cells in dynamic suspension,” 12th Annual Meeting of International Society for Stem Cell Research (ISSCR 2014), Vancouver, Canada, June 18-21, 2014.
  16. Castro, C., Rosillo C., and Tsutsui, H., “Characterizing wicking for development of paper-based analytical devices,” 2014 AAAS Pacific Division Annual Meeting, Riverside, CA, June 17-20, 2014.
  17. Nampe, D., Joshi, R., Beaudette, C., Liew, C.G., and Tsutsui, H., “Understanding how fluidic agitation impacts human pluripotent stem cells in dynamic suspension,” Clinical Translation of Stem Cells, Palm Desert, CA, April 21-22, 2014.
  18. Dixit, H.G., Nampe, D., Tsutsui, H., and Rao, M.P., “Optimizing performance of MEMS-based mechanoporation devices for ultrahigh throughput cellular manipulation”, 2014 ASME 3rd Global Congress on Nanoengineering for Medicine and Biology (NEMB 2014), San Francisco, CA, Feb. 2-5, 2014.
  19. Castro, C., Rosillo, and Tsutsui, H., "Manipulating channel properties in paper-based microfluidic devices to control fluid transport," 2013 ASME International Mechanical Engineering Congress and Exposition (IMECE 2013), San Diego, CA, Nov. 15-21, 2013.
  20. Dixit, H.G., Nampe, D., Zhang, Y., Ballas, C.B., Tsutsui, H., and Rao, M.P., "Optimizing performance of MEMS-based mechanoporation devices for ultrahigh throughput cellular manipulation," 2013 ASME International Mechanical Engineering Congress and Exposition (IMECE 2013), San Diego, CA, Nov. 15-21, 2013.
  21. Nampe, D., Beaudette, C., Liew, C.G., and Tsutsui, H., "Characterizing self-renewal of human pluripotent stem cells in dynamic suspension culture," 11th Annual Meeting of International Society for Stem Cell Research (ISSCR 2013), Boston, MA, June 12-15, 2013.
  22. Castro, C., Rosillo, C., Yoo, J., and Tsutsui, H., "Characterization of wax expansion and capillary wicking for paper-based microfluidics," 7th International Conference on Microtechnologies in Medicine and Biology (MMB 2013), Marina Del Rey, CA, April 10-12, 2013.
  23. Zhang, Y., Nampe, D., Dixit, H.G., Ballas, C.B., Tsutsui, H., and Rao, M.P., "Operational factors affecting performance of MEMS-based ultrahigh throughput mechanoporation devices," 7th International Conference on Microtechnologies in Medicine and Biology (MMB 2013), Marina Del Rey, CA, April 10-12, 2013.
  24. Nampe, D., Beaudette, C., Liew, C.G., and Tsutsui, H., "Optimization of chemical and physical factors toward clinically enabling culture of pluripotent stem cells," The 6th IEEE International Conference on Nano/Molecular Medicine and Engineering (NANOMED 2012), Bangkok, Thailand. November 4-7, 2012, pp.41-46.
  25. Hsu, N., Latterman, P., Tong, M., Tran, C., Wu, A., Ziv, M., and Tsutsui, H., "Self-assembled organic microwires as a new biosensor platform," BMES 2011 Annual Fall Meeting, Hartford, CT, October 12-15, 2011.
  26. Tsutsui, H., Valamehr, B., Wu, H., and Ho, C.M., “Stochastic optimization of small molecule inhibitor cocktails for human embryonic stem cell culture,” BMES 2009 Annual Fall Meeting, Pittsburgh, PA, October 7-10, 2009.
  27. Tsutsui, H., Yu, E., Marquina S., and Ho, C.M., “Dielectrophoretic patterning and assembly of mammalian cells using inert microstructure templates,” BMES 2009 Annual Fall Meeting, Pittsburgh, PA, October 7-10, 2009.
  28. Lillehoj, P., Li, N., Tsutsui, H., and Ho, C.M., “A compact microfluidic continuous flow separator for particle and cell sorting,” Proceedings of the 21st Annual IEEE International Conference on Micro-Electro-Mechanical Systems (MEMS’08), pp. 292 – 295, Tucson, AZ, January 13-17, 2008, pp.292-295.
  29. Tsutsui, H., Valamehr, B., Wu, H., and Ho, C.M., “Development of Embryoid Body Array toward Systematic Study of Stem Cell Differentiation,” BMES 2007 Annual Fall Meeting, Los Angeles, CA, September 26-29, 2007
  30. Tsutsui, H., Wu, H., and Ho, C.M., “Stable poly(ethylene glycol) microwell arrays for long-term cell patterning”, the 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS2006), Tokyo, Japan, November 5-9, 2006, pp. 242-244.
  31. Tsutsui, H., Wu, H., and Ho, C.M., “Directed differentiation of mouse embryonic stem cells in patterned microchannels”, The International Conference on Bio-Nano-Informatics (BNI) Fusion, Marina del Rey, USA, July 2005.
  32. Nomura, K.K., Tsutsui, H., Mahoney, D., Crockett, J., and Rottman, J.W., "Evolution of a counter-rotating vortex pair in a stably stratified fluid", Proc. of 3rd International Symposium on Turbulence and Shear Flow Phenomena, Sendai, June, 2003. pp. 769-774.
  33. Nomura, K.K., Mahoney, D., Tsutsui, H., Crockett, J., and Rottman, J.W., "Effects of stable stratification on the short wave instability in a vortex pair", Bull. Am. Phys. Soc., Vol. 46, No. 10, 2002.
  34. Tsutsui, H., Suzuki, Y., and Kasagi, N., "Development of electrostrictive polymer actuators for active control of turbulence", Proc. Meeting of Japan Society of Fluid Mechanics, July-August, 2001, pp.441-442.

Other Presentations

  1. Tsutsui, H., "Engineering culture system to control stem cell fate," Department of Mechanical Engineering, Chulalongkorn University, Bangkok, Thailand. November 7, 2012.

Patents

Coming soon